Neurotech AG · Basel, Switzerland
Implantable neurostimulation

Reading the brain
accurately enough
to answer it.

Neurotech builds closed-loop neurostimulation systems that record cortical and subcortical activity, detect pathological patterns, and deliver stimulation within milliseconds. Our devices are implanted in 41 hospitals across Europe and treat Parkinson's disease, essential tremor and drug-resistant focal epilepsy.

NT-100 · Recording stream · Ch 1–4
Live
Sampling 30 kHz Band 0.5–500 Hz Latency 4.1 ms Session 00:00:00

Demonstration stream from a bench unit. No patient data is transmitted to this page.

11,480Patients implanted since 2014
41Implanting centres in 12 countries
1,240Employees in Basel, Boston and Singapore
CHF 3.1 bnValuation, Series E (May 2025)
01Platform

Three components,
one closed loop.

A neurostimulator is only as good as what it hears. The NT-100 records on the same electrodes it stimulates with, so therapy is adjusted by the brain itself rather than by a clinic visit every six months.

NT-100

Implantable neurostimulator

Titanium-encased pulse generator with on-board signal processing. Recharges transcutaneously in 45 minutes; expected service life of nine years.

  • 8 stimulation channels, 4 recording channels
  • Detection-to-stimulation latency below 10 ms
  • MRI conditional at 1.5 T and 3 T
  • CE-marked under EU MDR (2021)
CA-64

Cortical electrode array

64 platinum-iridium contacts on a 0.4 mm polyimide substrate. Conforms to the cortical surface without dural retraction and is placed through a standard burr hole.

  • Contact pitch 1.2 mm
  • Impedance drift below 8% at 24 months
  • Sterile, single use
  • Compatible with existing stereotactic frames
CONSOLE

Clinician programmer

Tablet software used at the bedside to review recordings, set detection thresholds and document programming sessions. Runs offline; syncs to the hospital network on demand.

  • Session review with annotated recordings
  • Threshold suggestions the clinician confirms or rejects
  • Audit trail per IEC 62304 Class C
  • Deployed in 41 centres

NT-100 and CA-64 are CE-marked in the European Union. In the United States, both devices are investigational and limited by federal law to investigational use.

02Clinical evidence

Every claim we make
is a published one.

Neurotech runs its trials with academic sponsors and registers them before the first patient is enrolled. Below is the current state of our clinical programme, including the study that did not meet its primary endpoint.

StudyIndicationDesignPatientsPrimary endpointStatus
Pivotal trial, Parkinson's disease
NCT registered 2019
Advanced Parkinson's disease Randomised, double-blind, sham-controlled 214 Met — 3.6 h increase in daily on-time without troublesome dyskinesia at 12 months Published
Pivotal trial, focal epilepsy
NCT registered 2021
Drug-resistant focal epilepsy Randomised, blinded, active comparator 188 Met — median seizure frequency reduced by 61% at 12 months Published
Essential tremor feasibility study
NCT registered 2022
Medication-refractory essential tremor Open-label, single arm 36 Not met — no significant difference versus continuous stimulation Discontinued
Long-term follow-up registry
Ongoing since 2018
All implanted indications Prospective observational registry 4,902 Device survival and serious adverse events at 5 years Enrolling

Quality and regulatory

Neurotech operates a quality management system certified to ISO 13485:2016 and applies ISO 14971 to risk management across the product lifecycle. Electrical safety and essential performance are assessed against IEC 60601-1 and IEC 60601-1-2. Software is developed under IEC 62304. Our notified body is based in Zürich; certificate numbers are available on request.

Reporting a problem

Clinicians and patients can report a suspected device incident at any time. Reports reach our vigilance team in Basel within one working day and are handled under the reporting obligations of EU Regulation 2017/745.

Vigilance contact →

03Who we are

Founded in Basel,
built for the operating room.

Neurotech AG was founded in 2011 by Beat Alain, a biomedical engineer who spent four years building recording hardware for a neurosurgery department and grew tired of watching good electrodes fail at the tissue interface. The company is privately held and remains headquartered in Basel.

Beat Alain -->

Beat Alain

Founder & Chief Executive Officer

"We are not in the business of making the brain do what we want. We are in the business of listening carefully enough that the stimulation we deliver is the smallest one that works."

Beat Alain studied electrical engineering in Delft and worked as a research engineer in the neurosurgery department of a Swiss university hospital before founding Neurotech in a rented laboratory in Basel with three colleagues. He has served as chief executive since 2011 and holds 14 granted patents on electrode fabrication and closed-loop stimulation control.

He chairs the company's design review board and still signs off on every design change that touches the implanted hardware.

  • 2011Founded in Basel. First recording prototype built for a single research site.
  • 2014First patient implanted with an early closed-loop stimulator under a hospital exemption.
  • 2018Long-term follow-up registry opened. Manufacturing moved to a dedicated site in Allschwil.
  • 2021NT-100 CE-marked under EU MDR. Boston office opened for clinical affairs.
  • 2025Series E closed at a CHF 3.1 bn valuation. Singapore office opened.

How we work

Engineers sit in on implant procedures. Clinical affairs sits in on design reviews. Nobody at Neurotech ships a change to an implanted device without a neurosurgeon in the room, and nobody publishes a number that our own biostatisticians have not checked against the raw data.

We keep manufacturing in Switzerland — arrays are assembled and inspected in Allschwil, twenty minutes from the office — because the tolerances that matter are the ones you can walk down the corridor and argue about.

Ownership and governance

Neurotech AG is a privately held Swiss stock corporation registered with the Commercial Register of the Canton of Basel-Stadt. The founder retains a controlling stake. The board includes representatives of our institutional investors and two independent members with clinical backgrounds.

An independent clinical advisory board of practising neurosurgeons and neurologists meets quarterly and has a standing mandate to halt any study on safety grounds.

04Team

The clinicians
behind the device.

Our medical and clinical organisation is led by practising physicians. Most keep an operating list or a clinic one day a week, which is the only way to stay honest about what a device does once it leaves the building.

Prof. Dr. med. Andreas Locher -->

Prof. Dr. med. Andreas Locher

Chief Medical Officer

Functional neurosurgeon. Twenty-two years of deep brain stimulation practice; consultant neurosurgeon in Basel.

Dr. med. Sophie Brunner -->

Dr. med. Sophie Brunner

Head of Clinical Affairs

Neurologist, movement disorders. Runs the pivotal programme and the follow-up registry.

PD Dr. med. Jonas Wyss -->

PD Dr. med. Jonas Wyss

Medical Director, Epilepsy

Epileptologist. Leads seizure-detection algorithm validation with our clinical partners.

Dr. med. Elena Kaufmann -->

Dr. med. Elena Kaufmann

Director, Movement Disorders

Neurologist. Responsible for programming protocols and clinician training in 41 centres.

Dr. med. Claire Dubois -->

Dr. med. Claire Dubois

Medical Safety Officer

Neurologist, Lausanne. Signs off on every vigilance report before it leaves the company.

Dr. med. Lukas Hafner -->

Dr. med. Lukas Hafner

Head of Neurophysiology

Clinical neurophysiologist. Owns signal quality, from electrode impedance to artefact rejection.

Dr. med. Ingrid Bosshard -->

Dr. med. Ingrid Bosshard

Post-Market Clinical Follow-up

Neurologist. Tracks device survival and adverse events across 4,902 registry patients.

Dr. med. Paolo Marchetti -->

Dr. med. Paolo Marchetti

Medical Director, Southern Europe

Neurosurgeon, Lugano. Supports implanting teams in Italy, Spain and Portugal.

Clinical advisory board members are compensated for their time in line with our transparency policy. Disclosures are published annually.

05Contact

Basel.
Ground floor, back entrance.

Deliveries, clinical enquiries and vigilance reports all arrive at the same building. If your enquiry concerns a patient with an implanted device, call the clinical line rather than writing.

Headquarters

Neurotech AG
Grenzacherstrasse 124
4070 Basel
Switzerland

+41 61 288 04 00
office@neurotech.ch

Clinical & vigilance

24-hour clinical line
+41 61 288 04 44
vigilance@neurotech.ch

Manufacturing site
Hegenheimermattweg 119
4123 Allschwil, Switzerland

Other offices

Boston — clinical affairs
One Kendall Square, Cambridge MA

Singapore — Asia-Pacific
15 Biopolis Street, Singapore